A Compendium of tyrosine-kinase inhibitors: Powerful and efficient drugs against cancer

Abstract

The inhibitors of the enzymes tyrosine kinase (ITKs), also known by "tinibs", have been used as the most modern and effective tools in the treatment of several types of cancer. This article is a compilation of a huge series of tyrosine kinase inhibitors, recently approved or under clinical trials, containing in each of them information such as: The first chemical synthesis, the mechanism of action against cancer, clinical trials stage and price in the market.