Comparative investigation on antimicrobial and phytochemical profiling of cyclea peltata and tiliocora acuminate

Abstract

Antimicrobial drug resistance is a major problem in worldwide, because the resistance microbial pathogens are emerged due to its genetic plasticity. Over usage of inappropriate antibiotics rose as a prominent factor for the development of multidrug resistant organisms. From the ancient time itself, plants are used as a principal source for medicinal agent/ drugs, which are lesser side effect compared to the commercially available synthetic drugs. The usage of traditional medicines and its related medicinal plants are helps to lead a healthy life. Here, we use two medicinal valuable plants, such as Cyclea peltata and Tiliacora acuminate, to determine the antimicrobial resistance capacity using various solvents. In this paper, water extracts were not revealed that much of inhibition against human pathogens when compared with other solvents, like, C. peltata give well determined zone of inhibition against Bacillus subtilis by chloroform and Escherichia coli while using ethanol, whereas for using T. acuminata showed better activity against E. coli, Streptococcus pyogenes (ethanol) and Klebsiella pneumoniae, Pseudomonas aeruginosa and Staphylococcus aureus (chloroform).