Intrauterine insemination

Abstract

Intrauterine insemination is a first-line, noninvasive, and cost-effective assisted reproductive technique in selected cases. The sperm sample prepared from semen under laboratory conditions is transmitted directly to the upper uterine cavity. It can be applied in indications such as unexplained infertility, moderate male factor, and cervical factor. In the literature, the clinical success rate is stated to be between 10-20%. The purpose of sperm preparation is to isolate sperm from decapacitating factors, viral and bacterial residues in semen, to increase sperm motility and to provide sperm capacitation. A female patient can be subjected to a preapplication stimulation protocol. While stimulation increases the success rate of IUI, it also increases the risk of multiple pregnancy.