Total synthesis of azithromycin

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Abstract

The quaternary king: Azithromycin (1), which has improved pharmacological profiles compared with erythromycins, was the target of an enantioselective synthesis. All the stereogenic quaternary carbon centers were elaborated by a desymmetrization of 2-substituted glycerols using a chiral imine/CuCl 2catalyst. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

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APA

Kim, H. C., & Kang, S. H. (2009). Total synthesis of azithromycin. Angewandte Chemie - International Edition, 48(10), 1827–1829. https://doi.org/10.1002/anie.200805334

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