Correlation Between the Incidence of Drug-Related Problems (DRPs) and Clinical Outcomes in Type 2 Diabetes Mellitus Patients with Dyslipidemia at Central Hospital Dr. M. Djamil

Abstract

Effective management of diabetes therapy is a major challenge in the management of chronic conditions that are accompanied by comorbidities like dyslipidemia. The potential of unwanted events or Drug-Related Problems (DRPs) increases the emergence of comorbidities. This study aims to identify the correlation between the incidence of DRPs and clinical outcomes in patients with type 2 diabetes mellitus with dyslipidemia at Central Hospital Dr. M. Djamil Padang. The study was conducted by prospective method that used purposive sampling technique with 25 inpatients. Identification of DRPs used Pharmaceutical Care Network Europe (PCNE) version 8.01. Inclusion criterias were type 2 diabetes mellitus patient with dyslipidemia and also patients were prescribed at least one of antidiabetic or anti dyslipidemia drug. The results showed that there were several types of DRPs consist of inappropriate drug combinations (32%), untreated indications (20%), inappropriate timing and/or dosing intervals (12%), and too short duration (8 %). Statistical analysis showed that there was not significant correlation (p>0.05) between the incidence of DRPs and clinical outcomes in type 2 diabetes mellitus patients with dyslipidemia at Central Hospital Dr. M. Djamil Padang