Studies on the Antihemostatic Substances in Herbs Classified as Hemostatics in Traditional Chinese Medicine. I: On the Antihemostatic Principles in Sophora japonica L

Abstract

By following the antihemostatic activity of the material according to Tajima's method, the antihemostatic principle was isolated from dried buds of Sophora japonica L., and identified as isorhamnetin [2-(3-methoxy-4-hydroxyphenyl)-3,5,7-trihydroxy-4H-l-benzopyran-4-one]. The antihemostatic specificity of isorhamnetin toward antihemorrhagic compounds isolated previously from hemostatic herbs used in traditional Chinese medicine was examined. © 1989, The Pharmaceutical Society of Japan. All rights reserved.