Middle East Respiratory Syndrome - Corona Virus (MERSCoV): A Deadly Killer

Abstract

Middle east respiratory syndrome-corona virus ,a new species of corona virus has emerge in the middle east countries and has very high (almost 50%) fatality ratio. There is no any specific symptoms which are seen in the MERS-CoV. The symptoms which are seen are similar to those of simple general respiratory disease. There is no any treatment as well as no any vaccine available for the condition. Only one thing which are in our hand is to prevent the disease. Transmission of the disease is mainly by person to person transmission or by the virus affected bat or camels which are seen in the most of the cases. Disease is mostly seen in aged people (age>65) which has week immune system and which are under ICU or Dialysis are more prone to the disease. Phylogenetic analysis shows that the patients which have the disease they have directly or indirectly contact shows that person to person transmission occur in the MERS-CoV. The pathogenesis of the disease is still unknown. Clusters of cases in Saudi Arabia, Jordan, the UK, France, Tunisia, and Italy are being investigated. The genome sequence of the virus has identified and real time reverse transcriptase polymerase chain reaction(real time -RT-PCR) has important diagnostic tool for the identification of the disease. The WHO and CDC are currently working on the specific transmission pattern and finding the new scope of treatment and vaccine. There are specific prevention information for the patients, hospital staff, and visitors and the person who travels in the middle east countries guided by WHO and CDC. Key-words: MERS-CoV, beta-coronavirus, Middle East Respiratory Syndrome, novel coronavirus, London1_novel CoV