Abstract
Carboxylic acids are converted into the corresponding homologated acids or esters, using easily available 1-(trimethylsilylmethyl)benzotriazole (1) as a one-carbon synthon. The effectiveness of the reaction has been investigated on six aryl and seven alkyl carboxylic acids.
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CITATION STYLE
APA
Katritzky, A. R., Zhang, S., Haleem, A., Hussein, M., Fang, Y., & Steel, P. J. (2001). One-carbon homologation of carboxylic acids via BtCH2TMS: A safe alternative to the Arndt-Eistert reaction. Journal of Organic Chemistry, 66(16), 5606–5612. https://doi.org/10.1021/jo0017640
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