Tungsten-substituted molybdophosphoric acid impregnated with kaolin: effective catalysts for the synthesis of 3,4-dihydropyrimidin-2(1: H)-ones v i a biginelli reaction

Abstract

A series of highly reusable heterogeneous catalysts (10-25 wt% PMo7W5/kaolin), consisting of tungsten-substituted molybdophosphoric acid, H3PMo7W5O40·24H2O (PMo7W5) impregnated with acid treated kaolin clay was synthesized by the wetness impregnation method. The newly synthesized catalyst was fully characterized using inductively coupled plasma-atomic emission spectroscopy (ICP-AES), Fourier transform infrared (FT-IR), powder X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM), Brunauer-Emmett-Teller (BET) analysis and thermal analysis (TG-DTA). The synthesized materials were shown to be efficient in the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via Biginelli reaction under solvent-free conditions. The obtained results indicate that 20% PMo7W5/kaolin catalyst showed remarkably enhanced catalytic activity compared to the bulk PMo7W5 catalyst, and also the (10 and 15%) PMo7W5 catalyst supported on kaolin clay. This journal is