Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging

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Abstract

An MRI-responsive agent that spontaneously self-assembles to a large supramolecular structure under physiological conditions was designed. The obtained assembly provides an extended time window for in vivo studies, as demonstrated for a fluorine-19 probe constructed to sense Zn2+ with 19F-iCEST MRI, in the future.

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Tirukoti, N. D., Avram, L., Mashiach, R., Allouche-Arnon, H., & Bar-Shir, A. (2022). Self-assembly of an MRI responsive agent under physiological conditions provides an extended time window for in vivo imaging. Chemical Communications, 58(81), 11410–11413. https://doi.org/10.1039/d2cc03126d

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