Review article: sodium starch glycolate as a super disintegrant

Abstract

Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis, level used as superdisintegrant, different types of SSG’s and various physicochemical properties. SSG available as different brands i.e Primojel, Explotab and Vivastar with different properties. Excipient, generally considered as an inert component, are of great importance in drug product development. Interchange between different suppliers can lead to final products with different quality attributes