Synthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity

4Citations
Citations of this article
17Readers
Mendeley users who have this article in their library.
Get full text

Abstract

In this study, new nine pyrazoline derivatives were synthesized from chalcone derivatives. The antimicrobial activity of nine pyrazoline derivatives to four standard bacterial strains (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis) and four standard yeast strains (Candida albicans, Candida glabrata, Candida parapsilosis, Candida tropicalis) was investigated by the microdilution method for in accordance with the Clinical and Laboratory Standards Institute (CLSI) standard, and the Minimal Inhibitory Concentration (MIC) values of these derivatives were determined. Among these derivatives; compounds 7 and 8 against bacterial strains and compounds 2 and 3 against yeast strains exhibited good antimicrobial activity.

Author supplied keywords

Cite

CITATION STYLE

APA

Tok, F., Doğan, M. O., Gürbüz, B., & Koçyiğit-Kaymakçioğlu, B. (2022). Synthesis of novel pyrazoline derivatives and evaluation of their antimicrobial activity. Journal of Research in Pharmacy, 26(5), 1453–1460. https://doi.org/10.29228/jrp.238

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free