Preparation and characterization of zinc oxide nanoparticles

Abstract

In the present study, the zinc oxide nanoparticles (ZnO NPs) were prepared by using a sol-gel method. The characterization of ZnO NPs, such as particle size, morphology, crystal form, optical properties and pH-responsive behavior, was carried out. The in vitro anti-tumor activity of ZnO NPs was evaluated on PC-3M and 4T1 cell lines. The results indicated that ZnO NPs were spherical NPs with uniform particle size, excellent fluorescence properties, and pH-responsive behavior. The in vitro anti-tumor activity of ZnO NPs was observed on PC-3M and 4T1 cell lines. Considering to above characteristics, ZnO NPs could be used as drug delivery carries for loading active compound performing therapeutic and diagnostic effect.