Anticorpos contra o citoplasma de neutrófilos

Abstract

The discovery of the serological markers known as antineutrophil cytoplasmic antibodies revolutionized the diagnosis and followup treatment of the various forms of pulmonary vasculitis, especially that of Wegener's granulomatosis. The antineutrophil cytoplasmic antibodies pattern can be cytoplasmic or perinuclear. Determination of antineutrophil cytoplasmic antibodies titers aids the diagnosis and follow-up treatment of pulmonary vasculitis.