Formulation and evaluation of Herbal transdermal film

Abstract

Transdermal patch is a medicated adhesive pad that is designed to release the active ingredient at a constant rate over a period of several hours to days after application to the skin. It has been found that drugs from herbal origin can be utilized with enhanced efficacy by incorporating in transdermal drug patches. Transdermal drug delivery system (TDDS) thus offers a better route of delivery, reported to have better patient compliance. In the present work we tried to formulate and evaluate Nelumbo nucifera herbal patches. Nelumbo nucifera Gaertn (Nymphaeaceae), a perennial aquatic plant, has been used as a medicinal herb in China and India. It has been recorded in the most famous medicinal book in China for more than 400 years. The pharmacological studies have shown that N. nucifera posseses various notable pharmacological activities like anti-ischemic, antioxidant, anticancer, antiviral, antiobesity, lipolytic, hypocholestemic, antipyretic, hepatoprotective, hypoglycaemic, antidiarrhoeal, antifungal, antibacterial, anti-inflammatory and diuretic activities.