Comparative study of the clinical response of patients to different treatment regimens in rheumatoid arthritis

Abstract

There are different therapeutic solutions available for rheumatoid arthritis (RA) patients, suitable for different stages and different comorbidities. The outcome depends on both the patient’s clinical response and the therapeutic treatment chosen. The main clinical objectives are slowing the progression of disease and the effective management of patient symptoms, avoiding as far as possible the irreversible damage on the joints and cartilages. In this study we observed four different treatment strategies available and recommended in RA in terms of therapy response considering the stage of RA that the patients were in, as well. The strategies involved, included methotrexate in monotherapy, methotrexate combined with biological therapy, methotrexate and corticotherapy and methotrexate and physiokinetotherapy. Following this study, the most efficient statistically in the treatment response, were the patients included in the group of methotrexate combined with biological therapy.