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Regulating Stem Cell-Related Genes Induces the Plastic Differentiation of Cancer Stem Cells to Treat Breast Cancer

Molecular Therapy Oncolytics (2020) 18 396-408
DOI: 10.1016/j.omto.2020.07.009
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Abstract

Lu and his colleagues proposed a groundbreaking plastic differentiation concept, which was referred to inducing the cancer stem cells to differentiate into normal cells, dormant cells, and mature cancer cells by salinomycin, hence providing a likely novel strategy for cancer therapy.

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Zhang, J. Y., Luo, Q., Xu, J. R., Bai, J., Mu, L. M., Yan, Y., … Lu, W. L. (2020). Regulating Stem Cell-Related Genes Induces the Plastic Differentiation of Cancer Stem Cells to Treat Breast Cancer. Molecular Therapy Oncolytics, 18, 396–408. https://doi.org/10.1016/j.omto.2020.07.009

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