High-Entropy Alloys for Bone Tissue Engineering: Recent Developments in New Methods of Manufacture

Abstract

The demand for bone implants with superior biocompatibility and mechanical properties in bone tissue engineering is increasing due to rising demand for artificial bones and bone implant to replace degraded bones in human bodies. The causes of bone degradation in human bodies are not just due to rising number of road traffic accidents but are also due to disease burdens and injuries due to war and game activities. As a result, there is an urgent need to develop modern methods of manufacturing materials for implantable bone substitutes required in defective skeletal structures that cannot grow or heal on their own. It is believed that high-entropy alloys (HEAs) are best alternative materials for bone implants and development of modern methods for processing such materials could lead to manufacturing bone implants with the superior biocompatibility and mechanical properties. Therefore, this chapter examines the recent advances made in developing new methods for manufacturing bone implants using HEAs as raw materials. The chapter finally recommends the most appropriate methods for this purpose.