Z‐DNA as a probe for localized supercoiling in vivo

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Abstract

Biological processes such as transcription are expected to generate local variations in DNA super‐coiling. The existence of localized supercoiling was recently demonstrated in Escherichia coli by using the supercoil‐driven B‐to‐Z transition as a super‐helicity probe. This new methodology is described and its extension to other biological systems discussed. Copyright © 1992, Wiley Blackwell. All rights reserved

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Rahmouni, A. R. (1992). Z‐DNA as a probe for localized supercoiling in vivo. Molecular Microbiology. https://doi.org/10.1111/j.1365-2958.1992.tb01502.x

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