Rhodium-catalyzed (perfluoroalkyl)olefination of acetanilides leading to perfluoroalkylated aromatics

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Abstract

We have developed an efficient Rh-catalyzed (perfluoroalkyl)olefination reaction of acetanilides, which provides a versatile synthetic entry to a range of perfluoroalkylated compounds.

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Harada, K., Tezuka, N., Hirano, K., Miyamoto, K., Saito, T., & Uchiyama, M. (2016). Rhodium-catalyzed (perfluoroalkyl)olefination of acetanilides leading to perfluoroalkylated aromatics. Chemical and Pharmaceutical Bulletin, 64(10), 1442–1444. https://doi.org/10.1248/cpb.c16-00588

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