In the development of vaccines, the ability to initiate both innate and subsequent adaptive immune responses need to be considered. Live attenuated vaccines achieve this naturally, while inactivated and sub-unit vaccines generally require additional help provided through delivery systems and/or adjuvants. Liposomes present an attractive adjuvant/delivery system for antigens. Here, we review the key aspects of immunity against Plasmodium parasites, liposome design considerations and their current application in the development of a malaria vaccine.
CITATION STYLE
Ssemaganda, A., Giddam, A. K., Zaman, M., Skwarczynski, M., Toth, I., Stanisic, D. I., & Good, M. F. (2019). Induction of plasmodium-specific immune responses using liposome-based vaccines. Frontiers in Immunology. Frontiers Media S.A. https://doi.org/10.3389/fimmu.2019.00135
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