Comparative diclofenac detection for chronic toxicity levels using water soluble Zn-metalloporphyrin, gold nanoparticles and their hybrid

Abstract

The optical detection of chronic toxicity levels of diclofenac were comparatively investigated using novel nanostructured materials, such as: a water soluble metalloporphyrin: Zn(II)-tetra-(4-N-methyl-4-pyridyl)porphyrin tetrachloride (ZnTMePyP), tailored size spherical gold nanoparticles (n-Au) of 15-20 nm, and the hybrid nanomaterial (ZnTMePyP/n-Au) formed between them. After spectroscopic and microscopic analyses, it can be stated that the water soluble Zn-porphyrin alone can detect diclofenac in a larger domain of concentration (2.57 x 10-5-14.15 x 10-5 mol/L) than the hybrid formed between the metalloporphyrin and n-Au and that the gold nanoparticles alone are not capable of diclofenac detection.