Influence of addition of Al 2O 3 on physical, structural, acousticaland in-vitro bioactive properties of phosphate glasses

Abstract

Four different formulations of phosphate glasses in the system P 2O 5 -CaO-Na 2O-Al 2O 3 were developed. The elastic moduli have been obtained using the known method at room temperature. Their physicochemical and structural evolution was analyzed during in-vitro degradation in SBF (simulating body fluid) at 37 °C after 30 days. The results showed that the weight loss of the glass is greatly reduced with the incorporation of only 3 mol% of Al 2O 3 in P 2O5-CaO-Na2O glass composition. Fourier transform infrared (FTIR) spectroscopy performed on glasses before and after dipping in SBF showed calcium phosphate glasses in the system P 2O 25-CaO-Na 2O reinforced with Al 2O 3 offer an interesting option for slowlyresorbable materials as compared to other calcium phosphate glasses with high degradation velocity. The chemical formulation of these glasses allows the synthesis of materials with a controlled solubility. However, the substitution of Al 2O 3 5 mol% negatively affects the bioactivity of the P 2O 5 -CaO-Na 2O glasses. © 2009 WILEY-VCH Verlag GmbH &Co. KGaA.