Síndrome de Vogt-Koyanagi-Harada

Abstract

Vogt-Koyanagi-Harada disease is an infrequent, systemic syndrome that evolves in stages and compromises organs containing melanocytes. Typically, patients experience four different phases: meningoencephalitic, uveitic, convalescence with dermatologic involvement, and the chronic phase. Treatment of choice is high dose corticosteroids which may be combined with immunosuppressive agents. It should be initiated as early as possible to prevent eye damage. We present the case of a patient with the first two phases of the disease in addition to erythema multiform lesions. During convalescence phase, and in coincidence with the location of the latter, he developed vitiligo lesions that complete the syndrome.