A comprehensive review on spanules: A novel drug delivery system

Abstract

Spanules are considered one of the most advantageous drug delivery systems. Multi-drug regimen is the key benefit of Spanules (capsules having granules.) Spanules are constructed for the release of API (Drug) at different rates and times. The first immediate /slow-release pattern gives an initial drug release which is followed by drug release at a constant rate for an extended time.This will result in constantdrugsbeing available for a long time of period. This doses form is useful to overcome repeated drug dosing.