Structural studies of the O-specific side-chains of the shigella sonnei phase I lipopolysaccharide

Abstract

The structure of the O-specific side-chains of the Shigella sonnei phase I lipopolysaccharide has been investigated. The side chains are composed of disaccharide repeating-units containing two uncommon sugar components, one of witch, 2-amino-2-deoxy-L-altruronic acid, has been identified previously. The other has now been identified as 2-acetamido-4-amino-2,4,6-trideoxy-D-galactose. The uronic acid, as N-acetylated α-pyranosyl residues, is linked through O-4, and the diamino sugar, as β-pyranosyl residues, is linked through O-3. The pyranosyluronic acid residue assumes the 4C1 conformation in the polymer, with the carboxyl group in the axial position. © 1980.