Clinical Study of the Prunus dulcis (Almond) Shell Extract on Tinea capitis Infection

Abstract

Prunus dulcis (Almond) shell extract demonstrated for its biomedical applications. Shell extract prepared by soxhlet method and further characterized by UV-Visible spectrophotometer, Atomic Absorption Spectrophotometer (AAS) and MIC control method. In this study the antifungal activity of almond shell extract was observed against clinically isolated pathogenic fungus by strip method. The antioxidant potential of crude shell extract was also evaluated by using DPPH (2-2-diphenyl-1-picryhydrazyl) and radical scavenging system. The total antioxidant activity varied from 94.38 to 95.49% and total phenolic content was found 4.455 mg/g in almond shell extract. Finally the results provide a great therapeutic potential against infection of scalp caused by Tinea capitis and result can be achieved in 20 days therapy. In this study of shell extract results provide a great therapeutic potential against infection of scalp caused by Tinea capitis and provides scientific evidence for clinical efficacy against dermatologic disorders. The present study is aimed to summarize the therapeutic importance of cheap and discarded coconut shell and the future prospects in order to develop a new generation of modern antimycotic drugs.