MICRONEEDLES A POSSIBLE SUCCESSOR TECHNOLOGY FOR TDDS: A PATENT ANALYSIS

Abstract

The market size for transdermal drug delivery systems was assessed at USD 5.9 billion in 2020 and is expected to reach USD 8. 4 billion by 2028, expanding at a compound annual growth rate (CAGR) of 4.5% from 2021 to 2028. Micro Jet injectors, iontophoresis, electroporation, sonophoresis, microneedles, powdered injection, surface ablation, jet injectors and stripping by tape are some of the methods that enhance the delivery and ease of administration of larger molecules which is the major hindrance in case of Transdermal drug delivery system (TDDS). This type of delivery offers immediate delivery and avoids lag time. Microneedles are hollow cannulas inserted into the skin at 50 µm to 500 µm. The microneedle drug delivery systems market is projected to register a CAGR of 7.8% during the forecast period of 2022-2027. The microneedle drug delivery systems market is segmented by product type (solid, hollow, coated, and dissolvable), application (drug delivery, vaccine delivery, dermatology, and other applications), and geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America). This review summerizes the recent patents granted in the area of micro-needling in the year 2022 and also the commercial market of microneedles until now.