Obstetric outcomes of IVF trichorionic triamniotic triplets which are spontaneously or electively reduced to twins

Abstract

Purpose: To assess the obstetric outcome of IVF triplets which are spontaneously or electively reduced to twins. Methods: Retrospective study of trichorionic triplets (TT) and dichorionic twins (DT) conceived with IVF. Results: Compared to TT without reduction, TT with spontaneous reduction (SR) (OR: 5.6, 95% CI: 1.6-19.9) or elective reduction (ER) (OR: 14.0, 95% CI: 3.92-50.02) to twins were significantly more likely to be delivered at ≥34 weeks. Compared to DT likelihood of delivery ≥34 weeks was similar for SR and ER. Compared to TT without reduction, the risk of pregnancy loss before 24 weeks was not increased with SR or ER. Compared to DT the risk of pregnancy loss before 24 weeks was not significantly increased for SR or ER. Conclusion: Obstetric outcome of IVF triplets with SR is better than ongoing triplets and is similar to that of ER of TT and DT. © 2011 Springer Science+Business Media, LLC.