Stopping antidepressants

Abstract

Depressive illness is now recognised as a major health problem. As many patients do not need indefinite treatment, clinicians need to be aware of the symptoms associated with the discontinuation of antidepressants. Gradually reducing the dose is the best approach. Abrupt cessation of antidepressants should be avoided unless medical urgency necessitates it. Particular care is required when changing from one antidepressant to another.