ISOLATION AND CHARACTERIZATION OF FLAVONOID COMPOUND EXTRACTED CARDANTHERA DIFFORMIS DRUCE AND STUDY OF ITS ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES IN VITRO

Abstract

Human beings have been utilizing plants for basic preventive and curative health care since time immemorial. Medicinal plants have been used to treat illness and disease for thousands of years. Even now they are economically important, being used in the pharmaceutical, cosmetic, perfumery, and food industries. Screening of medicinal plants for antimicrobial activities and phytochems. is important for finding potential new compounds for therapeutic use. Humans are now struggling for their existence against different oxidative stress related diseases. Different meta-anal. suggests that poly-phenols, especially flavonoids, may play best protective role against this epidemiol. In this paper, an attempt has been made to present the results of the exptl. studies carried out to characterize a flavonoid compound that has been isolated and primarily identified from a plant extract of Cardanthera difformis Druce. The compound has similar physiochem. properties like quercetin. Antibacterial activity of extracted flavonoid has been carried out against various types of bacterial human pathogens. The result shows that the extract of Cardanthera difformis has a good anti-bacterial activity against Salmonella typhi. It has been found that this anti-bacterial flavonoid compound is good anti-oxidant compound and the anti-oxidant potentiality of the same has been quantified by DPPH-spectrophotometric assay.