Abstract
A new and simple method for a formal synthesis of (±)-lysergic acid (1), via a four-step sequence starting from the aldehyde (13), is described. A very high yield of the product was obtained after purification by column chromatography at the end of the process, without isolation of intermediates. © 1987, The Pharmaceutical Society of Japan. All rights reserved.
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Kurihara, T., Terada, T., Harusawa, S., & Yoneda, R. (1987). Synthetic Studies of (±)-Lysergic Acid and Related Compounds1). Chemical and Pharmaceutical Bulletin, 35(12), 4793–4802. https://doi.org/10.1248/cpb.35.4793
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