Functionalisation of 2-methoxy-6-methylpyridine

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Abstract

Selective bromination of 2-methoxy-6-methylpyridine 2 afforded 5-bromo-2-methoxy-6-methylpyridine 8. Deprotonation of this pyridine derivative in benzylic position or lithium-bromine exchange allowed the regio-selective introduction of various electrophiles. © 1994, Taylor & Francis Group, LLC. All rights reserved.

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Gray, M. A., Konopski, L., & Langlois, Y. (1994). Functionalisation of 2-methoxy-6-methylpyridine. Synthetic Communications, 24(10), 1367–1379. https://doi.org/10.1080/00397919408011740

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