Non-enzymatic glucose sensor based on three-dimensional hierarchical Co3O4 nanobooks

Abstract

A new non-enzymatic glucose sensor is demonstrated successfully, based on three-dimensional (3D) hierarchical Co3O4 nanobooks (Co3O4 NBs). The 3D hierarchical Co3O4 NBs are assembled with porous and high crystalline 2D Co3O4 nanosheets. The electrochemical measurements reveal that the device exhibits outstanding performance for glucose detection, achieving a maximal sensitivity of 1068.85 μA mM-1cm-2 with a high R2 of 0.9836, a low detection limit of 7.94 μM with a signal-to-noise of 3 and wide linear range up to 6 mM. The results demonstrate that the non-enzymatic glucose sensor can respond swiftly and selectively to glucose due to the high electrocatalytic activity of the 3D hierarchical Co3O4 NBs. The sensor also shows its high sensitivity and selectivity in detecting glucose in blood serum, confirming the practical application of the device with appealing accuracy.