A new guaiane mannoside from a Eutypa-like fungus isolated from Murraya paniculata in Brazil

Abstract

A Eutypa-like fungus was isolated from the stems of Murraya paniculata. The fungus was cultivated in liquid medium and produced the new guaiane-type sesquiterpenoid (1R,4S,5S,7R,10R)-10-hydroxyguaianol 10-O-β-mannopyranoside and the 3-hydroxy-5-phenylmethyl-(3S,5R)-tetrahydrofuran-2-one, a diastereomer of harzialactone A, obtained for the first time from a natural source. The structures of these metabolites were elucidated based on analysis of their spectroscopic data. ©2008 Sociedade Brasileira de Química.