Pyrethroid insecticides. Chapter III: Synthesis of 3-phenoxymandelonitrile

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Abstract

Racemic and enantiopure 3-phenoxymandelonitrile are valuable building blocks for the synthesis of pyrethrin insecticides cypermethrin and deltamethrin. Their synthesis involves two crucial steps: the synthesis of 3-phenoxybenzaldehyde which is produced through ether coupling, and its hydrocyanation.

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Krief, A. (2021). Pyrethroid insecticides. Chapter III: Synthesis of 3-phenoxymandelonitrile. Arkivoc. Arkat. https://doi.org/10.24820/ARK.5550190.P011.427

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