Process and laboratory scale UV inactivation of viruses and bacteria using an innovative coiled tube reactor

Abstract

Avoidance and elimination of viral contamination in biotechnological and pharmaceutical processes is a crucial issue. The novel UVivatec coiled tube reactor was designed for UV irradiation of cloudy liquid media. It very effectively inactivates especially critical viruses and avoids high product losses. The method proposed is an ideal complement to existing and established processes. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.