Novel Guaiane- and Secoguaiane-Type Sesquiterpenes from Alpinia japonica (Thunb.) Miq.

Abstract

Three novel guaiane-type sesquiterpenes, hanalpinone (I), isohanalpinone (II), and alpinenone (III), and two novel secoguaiane-type sesquiterpenes, alpinolide peroxide (IV) and 6-hydroxy-alpinolide (V) have been isolated from the rhizomes of Alpinia japonica. Their structures were determined by spectroscopic methods, chemical conversions, and X-ray analysis. Their biosynthetic relationships with previously identified sesquiterpenes from Alpinia japonica are discussed. © 1987, The Pharmaceutical Society of Japan. All rights reserved.