Red blood cell distribution width in dogs with chronic degenerative valvular disease

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Abstract

Objective-To evaluate RBC distribution width (RDW) in dogs with chronic degenerative valvular disease (CDVD) with compensated or decompensated heart failure. Design-Retrospective case-control study. Animals-27 healthy dogs and 135 dogs with CDVD (87 dogs with compensated heart failure and 48 dogs with decompensated heart failure). Procedures-The RDW and various CBC and serum biochemical variables were compared among groups. Correlations between RDW and various echocardiographic variables were evaluated. Results-Mean ± SD RDW in dogs with CDVD (13.1% ± 1.0%) was not significantly different from that of healthy dogs (12.8% ± 0.8%). The RDW of dogs with CDVD and compensated heart failure (13.0% ± 1.0%) was not significantly different from that of dogs with CDVD and decompensated heart failure (13.2% ± 1.1%). The RDW had a significant, weak, negative correlation with Hct (correlation coefficient, -0.250), hemoglobin concentration (correlation coefficient, -0.219), and mean corpuscular volume (correlation coefficient, -0.211). The RDW had a significant, weak, positive correlation with 1 echocardiographic index of CDVD severity (ie, the left atrium-to-aorta ratio [correlation coefficient, 0.183]). Conclusions and Clinical Relevance-In this study population, RDW did not seem to be associated with the presence of heart failure or CDVD.

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APA

Guglielmini, C., Poser, H., Pria, A. D., Drigo, M., Mazzotta, E., Berlanda, M., & Luciani, A. (2013). Red blood cell distribution width in dogs with chronic degenerative valvular disease. Journal of the American Veterinary Medical Association, 243(6), 858–862. https://doi.org/10.2460/javma.243.6.858

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