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Isoniazid metabolism and hepatotoxicity

Acta Pharmaceutica Sinica B
DOI: 10.1016/j.apsb.2016.07.014
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Abstract

Isoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations with INH-induced liver injury.

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Wang, P., Pradhan, K., Zhong, X. bo, & Ma, X. (2016, September 1). Isoniazid metabolism and hepatotoxicity. Acta Pharmaceutica Sinica B. Chinese Academy of Medical Sciences. https://doi.org/10.1016/j.apsb.2016.07.014

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