Electrodeposition of copper nanoparticles using pectin scaffold at graphene nanosheets for electrochemical sensing of glucose and hydrogen peroxide

Abstract

A simple electrodeposition approach has been described for the preparation of copper nanoparticles (CuNPs) using biopolymer pectin as a scaffold and graphene as a support. The formation of graphene/pectin-CuNPs was confirmed by scanning electron microscopy, UV-Visible spectroscopy and X-ray diffraction studies. The graphene/pectin-CuNPs film modified electrode was prepared and its electrocatalytic applications to the oxidation of glucose and reduction of H 2 O 2 have been explored. An amperometric glucose sensor was fabricated which exhibited excellent sensor performance in terms of wide linear range (10 μM-5.5 mM), low detection limit (2.1 μM) and high sensitivity (0.0457 μAμM -1 cm -2). Likewise, an amperometric sensor has been fabricated for the determination of H 2 O 2 which displayed linear range of 1 μM-1 mM, detection limit of 0.35 μM and sensitivity of 0.391 μAμM -1 cm -2. The sensor displayed appreciable repeatability, reproducibity and stability. Furthermore, practical feasibility of the sensor has been demonstrated in human serum and contact lens cleaning solution to determine glucose and H 2 O 2, respectively. The main advantages of sensor include simple and green fabrication approach, roughed and stable electrode matrix, high sensitivity and stability, fast in sensing and highly reproducible.