AFM and Fe-SEM imaging applications of functionalized carbon nanotubes in drug delivery systems of folic acid

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Abstract

Surface-prepared multifunctional drug delivery system from reagent with multi-walled carbon nanotubes, CdS, Fe3O4, and folic acid. The development of efficient and targeted drug delivery systems is an important area of research in biomedical engineering and nanomedicine. In this study, we propose a novel multifunctional drug delivery system using a surface prepared from a reagent mixture of multi-walled carbon nanotubes (MWCNTs), cadmium sulfide (CdS) nanoparticles, iron oxide nanoparticles (Fe3O4) and folic acid. Fabrication of a drug delivery system involves the synthesis of MWCNTs-CdS-Fe3O4 hybrid nanocomposites through a simple and scalable process. Folic acid is conjugated to the surface of nanocomposites using a bioconjugation strategy. The drug payload is deposited on the nanocomposite surface through physical or chemical adsorption, taking advantage of the nanotube structure and surface chemistry. Including controlled drug release, and active targeting through folic acid, make it a versatile platform for personalized medicine and cancer therapies. The ternary compound was investigated using atomic force microscopy (AFM), field emission scanning electron microscopy (FE-SEM), and FT_IR.

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Kadam, Z. M., & Flieh, S. S. (2024). AFM and Fe-SEM imaging applications of functionalized carbon nanotubes in drug delivery systems of folic acid. In AIP Conference Proceedings (Vol. 3097). American Institute of Physics. https://doi.org/10.1063/5.0213297

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