An efficient procedure to obtain hexahydroquinoleines and unsymmetrical 1,4-dihydropyridines using solid inorganic supports and microwave activation

Abstract

Satisfactory yields have been obtained in a one pot synthesis of hexahydroquinoleines and unsymmetrical 1,4-dihydropyridines using acidic or basic alumina respectively using catalytic DMF under microwave activation. Results were compared with those obtained following the classical method. The advantages obtained by the use of microwave irradiation were demonstrated.