Carbon materials for immobilization of biologically active substances

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Abstract

The paper considers applications of carbon materials as carriers of biologically active substances. The atomic layer deposition method allowed chemically synthesizing surface-modified composite materials based on graphite and carbon fibers, which maximally preserved the activity of enzymes and biologically active substances. The synthesis process of a mono-layer titaniumcontaining coating on the surface of graphite and carbon fibers by processing them with TiCl4 vapors is considered. The main characteristics of the graphite surface before and after modification and characteristics of the porous structure and surface of carbon fibers are obtained. Biologically active substances by adsorption from a solution to the surface of both the original and modified carriers were applied. biological activity and temperature stability of the obtained composite materials were studied. It is shown that the activity of a biologically active substance depends on the chemical composition and state of the surface of carbon-based carriers.

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Denisova, O. V., & Rastvorova, I. I. (2020). Carbon materials for immobilization of biologically active substances. In Key Engineering Materials (Vol. 836 KEM, pp. 52–57). Trans Tech Publications Ltd. https://doi.org/10.4028/www.scientific.net/KEM.836.52

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