Prostate cancer with supraclavicular lymphadenopathy and bulky abdominal tumor

Abstract

A 73-year-old man with suspected lymphoproliferative disorder was introduced to our hospital. The patient demonstrated palpable hard masses in the abdomen. Enhanced computed tomography of the abdomen and pelvis revealed a bulky mass of para-aortic lymph nodes. Biopsy of left-sided supraclavicular lymph nodes revealed metastatic adenocarcinoma. Serum tumor markers were examined, revealing prostate-specific antigen (PSA) levels of 3,354.0 ng/ml. Rectal examinations revealed a stony-hard prostatic mass. Biopsy of the prostate disclosed poorly to moderately differentiated adenocarcinoma. Although metastases to the supraclavicular lymph nodes are rare in prostate cancer, it should be distinguished from malignant lymphoma and other malignancies lignancies. © 2007 The Japanese Society of Internal Medicine.