We aimed at observing the association of a common genetic variant near the INSIG2 gene (rs7655505) with body mass index (BMI) related obesity in a population-based association study in Uyghur population. We observed a significant association of rs7566605 polymorphism with BMI related obesity in Uyghurs with an odds ratio of 1.47 (95% CI 1.11-1.95, P = 0.006) under a dominant model (CC + GC versus GG). The mean BMI of rs7566605 CC + GC was 0.59 kg/m2 higher than for GG genotype (P = 0.024), regardless of sex and age. © 2008 Elsevier Ireland Ltd. All rights reserved.
Mendeley helps you to discover research relevant for your work.
CITATION STYLE
Zhang, J., Lin, R., Wang, F., Lu, M., Lin, R. yong, Wang, S. zhen, … Wang, X. feng. (2008). A common polymorphism is associated with body mass index in Uyghur population. Diabetes Research and Clinical Practice, 81(2). https://doi.org/10.1016/j.diabres.2008.03.022