Ganglioneuroma originating from the trigeminal nerve in the middle cranial fossa

Abstract

A 55-year-old man present with a case of ganglioneuroma manifesting as sudden onset of severe headache. T1-weighted magnetic resonance imaging demonstrated a heterogeneously enhanced mass (3 ×3×2.5cm) in the left middle cranial fossa compressing the left cavernous sinus. The tumor was totally removed through a frontozygomatic approach. The histological diagnosis was ganglioneuroma originating from the second division of the trigeminal nerve in the middle cranial fossa. Ganglioneuroma can occur wherever ganglion cells exist, but ganglioneuroma originating from the trigeminal nerve is rare, with only two cases reported.