Homologe und heterologe Produktion von Bacteriocinen mit Corynebakterien

Abstract

Bacteriocins are gene-encoded antimicrobial peptides produced naturally by a wide range of bacteria. Their biological role is to provide producers with a competitive advantage over other bacteria in complex and densely populated habitats. Due to the dramatic increase in antibiotic resistances of many important pathogenic bacteria, bacteriocins are also discussed as potential alternatives to antibiotics. Here we discuss the potential of the members of the Corynebacteriaceae as a source for novel bacteriocins and as hosts for biotechnological production.