Vitreomacular traction after dexamethasone intravitreal implant (OZURDEX) injection: The effect of anomalous posterior vitreous detachment

Abstract

Purpose: To describe an unusual macular complication after dexamethasone intravitreal implant (Ozurdex) injection. Methods: Case history and macular optical coherence tomography findings are described. The report describes a patient with proliferative diabetic retinopathy and vitreoschisis who received Ozurdex treatment for diabetic macular edema. Results: After Ozurdex injection, visual acuity worsened because of newly formed vitreomacular traction that was demonstrated on optical coherence tomography imaging. A mechanism is proposed by which the medication might have contributed to this outcome. Conclusion: In this patient with vitreoschisis, a thickened posterior hyaloid membrane and traction developed after Ozurdex injection. The authors recommend careful evaluation of the macula before injection, particularly in diabetic patients with vitreoschisis.