Ehlers-Danlos Syndrome: Associated with Prematurity and Premature Rupture of Foetal Membranes; Possible Increase in Incidence

Abstract

Eighteen patients with Ehlers-Danlos syndrome were studied, and their circumstances of birth are reported in this paper. Fourteen patients (78%) were born prematurely, owing to premature rupture of the foetal membranes. Most-of the non-premature births occurred in one large exceptional family. It seems likely that there will be an increase in the number of patients surviving with Ehlers-Danlos syndrome in those countries which provide good antenatal and premature-infant care. © 1966, British Medical Journal Publishing Group. All rights reserved.